The Evidence Standard
Science Is the Luxury
Every formula begins in peer-reviewed literature, and earns its label through three verification gates.
From Molecule
to Protocol
A St. Lloyd formula is not a blend; it is a sequenced protocol. Ingredients are selected for pathway synergy, dosed to clinical relevance, and delivered in bioavailable forms.
- Human clinical evidence, never animal-only studies
- Clinical dosing, the exact quantities studied, declared openly
- Bioavailable forms, methylated B12, chelated minerals, phytosomes
- Pathway synergy, designed interactions, not ingredient soup
Three Gates. No Exceptions.
Human Evidence
Every hero ingredient must be supported by randomized, placebo-controlled human trials at the dose we deliver. Trendy without data doesn't ship.
Source Integrity
Pharmaceutical-grade and trademarked raw materials (Niagen®, KSM-66®) with certificates of analysis at the ingredient level, before manufacturing ever begins.
Batch Verification
Finished batches are tested by independent ISO-accredited laboratories for identity, purity, heavy metals, and microbial safety. Every single batch.
Inside the Flagship
The GLP-1 Companion Stack™, pathway by pathway.
Meta-analyses of rapid weight loss show 25–40% of lost mass can be lean tissue. HMB (β-hydroxy β-methylbutyrate) at 1.5–3 g/day has demonstrated anti-catabolic effects in caloric deficit, while creatine supports phosphocreatine energy reserves that preserve training intensity, the primary stimulus for muscle retention.
Chromium picolinate supports insulin receptor signaling and has been studied for cravings modulation. Berberine activates AMPK, the cell's master metabolic switch, with human trials showing support for healthy glucose and lipid metabolism already in normal range.
Reduced food intake on GLP-1 therapy reduces vitamin and mineral intake proportionally. We use methylcobalamin (active B12) and amino-acid-chelated magnesium and zinc, forms selected for absorption when gastric physiology is altered. A digestive enzyme matrix supports the absorption pathway itself.
Raw materials: identity + purity via HPLC/FTIR. Manufacturing: GMP 21 CFR Part 111 compliance with in-process verification. Finished batches: potency, heavy metals (Pb, As, Cd, Hg), and microbial panels by independent ISO-17025 laboratories. Certificates available at support@stlloyd.com.
Selected Clinical References
- Nissen S, et al. β-hydroxy-β-methylbutyrate supplementation and lean mass preservation. J Appl Physiol.
- Jastreboff AM, et al. Tirzepatide once weekly for the treatment of obesity. N Engl J Med 2022;387:205-216.
- Trammell SA, et al. Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nat Commun 2016;7:12948.
- Chandrasekhar K, et al. A prospective, randomized double-blind study of KSM-66 ashwagandha on stress. Indian J Psychol Med 2012.
- Vincent JB. The nutritional biochemistry of chromium(III). J Nutr Biochem.
- Haas MC, et al. Zinc carnosine and gastric mucosal integrity. Dig Dis Sci.
References provided for educational context. Full citations available on request.